An artificial knee replacement is done when a knee is
severely damaged by injury or disease. The most common condition that
results in the need for knee replacement surgery is osteoarthritis is the
main cause for knee replacement surgery. Hip replacement, also hip
arthroplasty, is a surgical procedure in which the hip joint is replaced by
a prosthetic implant, a surgical procedure that re-forms the hip-joint.
Shoulder Joint Replacement is a surgical method in which the diseased and
damaged parts of the shoulder joint are removed and replaced by an
artificial joint or a prosthetic joint.
Knee Replacement
Knee replacement, Arthroplasty or Computer Assisted Surgery for Joint
Replacement (CASJR) is a surgical procedure to replace a damaged knee with a
prosthesis (an artificial joint). This surgery may be considered for someone
who has severe arthritis or a severe knee injury.
The most common cause of chronic knee pain and disability is arthritis.
Osteoarthritis, rheumatoid arthritis, and traumatic arthritis are the most
common forms.
Total Knee Replacement is considered in the following conditions:
- Severe daily pain
- Pain is severe enough to restrict work, recreation and daily living
- Significant stiffness of the knee
- Significant instability of the knee
- Deformity of the knee (lock-knees or bowlegs)
Total Hip Replacement / Partial Hip Replacement
A Total Hip Replacement (THR) - also called a Hip Arthroplasty is a
surgical procedure that re-forms the hip-joint.
Osteoarthritis of the hip is the most common diagnosis that leads to hip
replacement. Osteoarthritis is caused by wear and tear. It affects the
cartilage surfaces of the ball-and-socket joint of the hip. The cartilage
wears out. Pain and stiffness result. Patients with hip arthritis have
difficulty walking, climbing stairs and performing routine daily activities.
Other conditions that can cause destruction of the hip joint include:
- Loss of blood supply to the head of the thighbone
- Rheumatoid arthritis (an inflammatory autoimmune disease)
- Previous injury or trauma
- Infection
- Developmental abnormalities in the hip
Bone Marrow Transplant
Major hospitals in India have oncology units comprising surgical oncology,
medical and radiation there by as well as the crucial Bone Marrow
Transplantation (BMT). The BMT unit with high pressure hipa filers has
helped achieve a very high success rate in the various types of
transplantation.
What is bone marrow?
The bone marrow is a soft, spongy tissue e found inside the bones. The bone
marrow in the hips, breast bone, spine, ribs, and skull contain cells that
produce the body's blood cells. The bone marrow is responsible for the
development and storage of about 95 percent of the body's blood cells. The
three main types of blood cells produced in the bone marrow include:
- Red blood cells (Erythrocytes) - carry oxygen to the tissues in the
body
- White blood cells (Leukocytes) - help fight infections and to aid in
the immune system
- Platelets - help with blood clotting
Each of these cells carries a life-maintaining function. The bone
marrow is a vital part of the human body.
Different types of bone marrow transplants
There are different types of bone marrow transplants depending on who the
donor is. The different types of bone marrow transplant include the
following:
Autologous bone marrow transplant
The donor is the child him/herself. Stem cells are taken from the child
either by bone marrow harvest or apheresis (peripheral blood stem cells) and
then given back to the child after intensive treatment. Often the term "rescue"
is used instead of "transplant."
Allogeneic bone marrow transplant
The donor shares the same genetic type as the child. Stem cells are taken
either by bone marrow harvest or apheresis (peripheral blood stem cells)
from a genetically-matched donor, usually a brother or sister. Other donors
for allogeneic bone marrow transplants include:
- A parent - a haploid-identical match is when the donor is a parent
and the genetic match is at least half identical to the recipient.
- An identical twin - a syngeneic transplant is an allogeneic
transplant from an identical twin. Identical twins are considered a
complete genetic match for a marrow transplant.
- Unrelated bone marrow transplants (UBMT or MUD for matched unrelated
donor) - the genetically matched marrow or stem cells are from an
unrelated donor. Unrelated donors are found through the national bone
marrow registries.
Umbilical cord blood transplant
Stem cells are taken from an umbilical cord immediately after delivery of
an infant. These stem cells reproduce into mature, functioning blood cells
quicker and more effectively than do stem cells taken from the bone marrow
of another child or adult. The stem cells are tested, typed, counted, and
frozen until they are ready to be transplanted.
Because the stem cells are "new," they are able to produce more
blood cells from each stem cell. Another advantage cord blood has is that
the T-lymphocytes (part of the immune system that causes graft-versus-host
disease) are not completely functional this early in the stage of life.
Recipients of cord blood transplants have a decrease risk for severe
graft-versus-host disease.